References

Agarwal R, Teoh S, Short D, Harvey R, Savage PM, Seckl MJ. Elevated human chorionic gonadotrophin levels six months after uterine evacuation of molar pregnancy- is chemotherapy necessary? A retrospective cohort study. Lancet Mar 13;106(6):1089-94

Alifrangis C, Agarwal R, Short D, Fisher RA, Sebire NJ, Harvey R, Savage PM, Seckl MJ. EMA/CO for high-risk gestational trophoblastic neoplasia: good outcomes with induction low-dose etoposide-cisplatin and genetic analysis. J Clin Oncol; 31(2):280-6

Bagshawe KD Risk and prognostic factors in trophoblastic neoplasia Cancer. 1976 Sep;38(3):1373-85

Bagshawe KD, Dent J, Webb J Hydatidiform mole in England and Wales 1973-83 Lancet. 1986 Sep 20;2(8508):673-7

Bagshawe KD, Dent J, Newlands ES, Begent RH, Rustin GJ. The role of low-dose methotrexate and folinic acid in gestational trophoblastic tumours (GTT) Br J Obstet Gynaecol. 1989 Jul;96(7):795-802

Bower M, Newlands ES, Holden L, Short D, Brock C, Rustin GJ, Begent RH, Bagshawe KD EMA/CO for high-risk gestational trophoblastic tumors: results from a cohort of 272 patients J Clin Oncol. 1997 Jul;15(7):2636-43

Bower M, Rustin GJ, Newlands ES, Holden L, Short D, Foskett M, Bagshawe KD Chemotherapy for gestational trophoblastic tumours hastens menopause by 3 years Eur J Cancer. 1998 Jul;34(8):1204-7

Braga A, Maestá I, Short D, Savage P, Harvey R, Seckl MJ. Hormonal contraceptive use before hCG remission does not increase the risk of gestational trophoblastic neoplasia following complete hydatidiform mole: a historical database review. BJOG. 2015 Oct 7.

Cole LA, Khanlian SA Inappropriate management of women with persistent low hCG results J Reprod Med. 2004 Jun;49(6):423-32

Cole LA, Shahabi S, Butler SA, Mitchell H, Newlands ES, Behrman HR, Verrill HL Utility of commonly used commercial human chorionic gonadotropin immunoassays in the diagnosis and management of trophoblastic diseases Clin Chem. 2001 Feb;47(2):308-15

FIGO Oncology Committee FIGO staging for gestational trophoblastic neoplasia 2000. FIGO Oncology Committee Int J Gynaecol Obstet. 2002 Jun;77(3):285-7

Fisher RA, Lavery SA, Carby A, Abu-Hayyeh S, Swingler R, Sebire NJ, Seckl MJ. What a difference an egg makes. Lancet Dec 3;378(9807):1974

Kaur B, Short D, Fisher RA, Savage PM, Seckl MJ, Sebire NJ. Atypical Placental Site Nodule (APSN) and Association With Malignant Gestational Trophoblastic Disease; A Clinicopathologic Study of 21 Cases. Int J Gynecol Pathol. 2015 Mar;34(2):152-8

Kurman RJ, Scully RE, Norris HJ Trophoblastic pseudotumor of the uterus: an exaggerated form of “syncytial endometritis” simulating a malignant tumor Cancer. 1976 Sep;38(3):1214-26

Mangili G, Lorusso D, Brown J, Pfisterer J, Massuger L, Vaughan M, Ngan HY, Golfier F, Sekharan PK, Charry RC, Poveda A, Kim JW, Xiang Y, Berkowtiz R, Seckl MJ. Trophoblastic disease review for diagnosis and management: a joint report from the International Society for the Study of Trophoblastic Disease, European Organisation for the Treatment of Trophoblastic Disease, and the Gynecologic Cancer InterGroup. Int J Gynecol Cancer. 2014 Nov;24(9 Suppl 3):S109-16

McNeish IA, Strickland S, Holden L, Rustin GJ, Foskett M, Seckl MJ, Newlands ES Low-risk persistent gestational trophoblastic disease: outcome after initial treatment with low-dose methotrexate and folinic acid from 1992 to 2000. J Clin Oncol. 2002 Apr 1;20(7):1838-44

Newlands ES, Bagshawe KD, Begent RH, Rustin GJ, Holden L Results with the EMA/CO (etoposide, methotrexate, actinomycin D, cyclophosphamide, vincristine) regimen in high risk gestational trophoblastic tumours, 1979 to 1989. Br J Obstet Gynaecol. 1991 Jun;98(6):550-7.

Newlands ES, Mulholland PJ, Holden L, Seckl MJ, Rustin GJ Etoposide and cisplatin/etoposide, methotrexate, and actinomycin D (EMA) chemotherapy for patients with high-risk gestational trophoblastic tumors refractory to EMA/cyclophosphamide and vincristine chemotherapy and patients presenting with metastatic placental site trophoblastic tumors J Clin Oncol. 2000 Feb;18(4):854-9

Newlands ES, Holden L, Seckl MJ, McNeish I, Strickland S, Rustin GJ Management of brain metastases in patients with high-risk gestational trophoblastic tumors J Reprod Med. 2002 Jun;47(6):465-71

Openshaw MR, Harvey RA, Sebire NJ, Kaur B, Sarwar N, Seckl MJ, Fisher RA. Circulating Cell Free DNA in the Diagnosis of Trophoblastic Tumors. EBioMedicine. 2015 Dec 29;4:146-52.

Papadopoulos AJ, Foskett M, Seckl MJ, McNeish I, Paradinas FJ, Rees H, Newlands ES Twenty-five years’ clinical experience with placental site trophoblastic tumors J Reprod Med. 2002 Jun;47(6):460-4

Paradinas FJ The diagnosis and prognosis of molar pregnancy: the experience of the National Referral Centre in London Int J Gynaecol Obstet. 1998 Apr;60 Suppl 1:S57-64

Rustin GJ, Newlands ES, Lutz JM, Holden L, Bagshawe KD, Hiscox JG, Foskett M, Fuller S, Short D Combination but not single-agent methotrexate chemotherapy for gestational trophoblastic tumors increases the incidence of second tumors J Clin Oncol. 1996 Oct;14(10):2769-73

Savage PM, Sita-Lumsden A, Dickson S, Iyer R, Everard J, Coleman R, Fisher RA, Short D, Casalboni S, Catalano K, Seckl MJ. The relationship of maternal age to molar pregnancy incidence, risks for chemotherapy and subsequent pregnancy outcome. J Obstet Gynaecol. 2013 May;33(4):406-11

Savage P, Kelpanides I, Tuthill M, Short D, Seckl MJ. Brain metastases in gestational trophoblast neoplasia: An update on incidence, management and outcome. Gynecol Oncol. 2015 Jan 15

Savage P, Cooke R, O’Nions J, Krell J, Kwan A, Camarata M, Dancy G, Short D, Seckl MJ, Swerdlow A. Effects of single-agent and combination chemotherapy for gestational trophoblastic tumors on risks of second malignancy and early menopause. J Clin Oncol. 2015 Feb 10;33(5):472-8

Schmid P, Nagai Y, Agarwal R, Hancock BW, Savage PM, Sebire NJ, Lindsay I, Wells M, Fisher RA, Short D, Newlands ES, Wischnewsky MB, Seckl MJ. Prognostic markers and long-term outcome of placental-site trophoblastic tumours: a retrospective observational study. Lancet 2009  Jul 4;374(9683):6-7

Sebire NJ, Foskett M, Fisher RA, Rees H, Seckl M, Newlands E. Risk of partial and complete hydatidiform molar pregnancy in relation to maternal age BJOG. 2002 Jan;109(1):99-102

Seckl MJ, Fisher RA, Salerno G, Rees H, Paradinas FJ, Foskett M, Newlands ES Choriocarcinoma and partial hydatidiform moles Lancet. 2000 Jul 1;356(9223):36-9.

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Seckl MJ, Sebire NJ, Fisher RA, Golfier F, Massuger L, Sessa C; ESMO Guidelines Working Group. Gestational trophoblastic disease: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2013 Oct;24 Suppl 6:vi39-50

Sita-Lumsden A, Short D, Lindsay I, Sebire NJ, Adjogatse D, Seckl MJ, Savage PM. Treatment outcomes for 618 women with gestational trophoblastic tumours following a molar pregnancy at the Charing Cross Hospital, 2000-2009. Br J Cancer. 2012 Nov 20;107(11):1810-4

Sita-Lumsden A, Medani H, Fisher R, Harvey R, Short D, Sebire N, Savage P, Lim A, Seckl MJ, Agarwal R. Uterine artery pulsatility index improves prediction of methotrexate resistance in women with gestational trophoblastic neoplasia with FIGO score 5-6. BJOG. 2013 Jul;120(8):1012-5.

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Wang J, Short D, Sebire NJ, Lindsay I, Newlands ES, Schmid P, Savage PM, Seckl MJ. Salvage chemotherapy of relapsed or high-risk gestational trophoblastic neoplasia (GTN) with paclitaxel/cisplatin alternating with paclitaxel/etoposide (TP/TE). Ann  Oncol. 2008 Sep;19(9):1578-83.

Wenzel L, Berkowitz RS, Newlands E, Hancock B, Goldstein DP, Seckl MJ, Habbal R, Bernstein M, Kluhsman B, Kulchak-Rahm A, Strickland S, Higgins J Quality of life after gestational trophoblastic disease J Reprod Med. 2002 May;47(5):387-94.

Wenzel L, Berkowitz R, Robinson S, Bernstein M, Goldstein D The psychological, social, and sexual consequences of gestational trophoblastic disease Gynecol Oncol. 1992 Jul;46(1):74-81.

Williams J, Short D, Dayal L, Strickland S, Harvey R, Tin T, Savage PM, Seckl MJ.  Effect of early pregnancy following chemotherapy on disease relapse and fetal outcome in women treated for gestational trophoblastic neoplasia. J Reprod Med. 2014 May-Jun;59(5-6):248-54

 

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